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Arbor Research Collaborative for Health is happy to announce the addition of Dr. Christine Stanik, PhD to their team of scientific researchers. Dr. Stanik holds a PhD in Social Psychology from the University of Michigan and officially joined Arbor Research on January 30, 2023. She is a social and developmental psychologist with 15 years of experience conducting quantitative and qualitative research to improve both health and well-being. Her work will focus on projects primarily housed in the Health Policy and Practice Program and will help Arbor Research broaden its portfolio across Health and Human Services (HHS).
“Our research team here at Arbor Research is a collection of some of the best and brightest, and Christine brings a wealth of experience and expertise that is a fantastic fit to our current research and future projects”, says Jeffrey Pearson, Director of the Health Policy & Practice Program at Arbor Research Collaborative for Health. “Her expertise and knowledge in long-term care and behavioral health will enhance our current projects and help us expand into new research.”
Before joining Arbor Research, Dr. Stanik led a variety of grants and contracts at Altarum. She is an expert in qualitative, quantitative, and mixed methods research with a strong track record of securing funding and delivering on health-related research projects. Her work covers a range of important topics including elder care, adolescent health, and behavioral health work and has been funded by the Agency for Healthcare Research and Quality (AHRQ), the Michigan Health Endowment Fund, Administration for Community Living (ACL), and the Centers for Medicare & Medicaid Services (CMS).
“The future direction of Arbor Research is of great interest to me, and I look forward to making contributions to further its mission impact. I’ve spent my career dedicated to seeking social determinants and interventions that improve the behavioral health and welfare of vulnerable populations”, says Dr. Christine Stanik. “I’m really looking forward to working with the Arbor Research team as we expand our reach.”
Individuals with BSEP deficiency with one p.E297G or p.D482G mutation and one PPTM have a similarly severe disease course and low responsiveness to siEHC as those with two PPTMs.
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Using a mouse model of BA and human liver gene expression data collected by ChiLDReN, we were able to confirm the likely activation of this pathway known as TWEAK/FN14 in association with liver fibrosis. We further showed that inhibition of this pathway pharmacologically was associated with near complete elimination of fibrosis in the mouse model of BA.